題目：Conjugated Polyelectrolyte as a New Platform for Biological Sensing and Imaging
報(bào)告人：劉斌博士（新加坡國立大學(xué)）
日期及時(shí)間：2009 年11 月20 日16 時(shí)30 分
地點(diǎn)：研究生樓－103
報(bào)告內(nèi)容摘要：
There is an increasing trend of using light-harvesting conjugated polyelectrolytes as signal reporters or signal amplifiers for chemical and biological detection. Cationic conjugated polyelectrolytes (CCP) in conjunction with dye labeled peptide nucleic acid probes have been used for sequence specific DNA detection with high sensitivity and selectivity. The signal output is largely dependent on the signal amplification provided by the CCP, which is greatly affected by the energy transfer efficiency between the CCP and the dye. In this talk, we will discuss different strategies to improve the fluorescent signal output and detection sensitivity for several DNA and protein assays. In addition, our recent progress of using CCPs for imaging and real-time naked eye detection and quantification of chemical and biological molecules will also be discussed.
報(bào)告人簡介： Bin Liu obtained BSc and MSc in organic chemistry from Nanjing University, China in 1995 and 1998. She earned her PhD degree in polymer chemistry from the National University of Singapore (NUS) in 2001. Following postdoctoral work at the University of California, Santa Barbara, she joined NUS in 2005. Dr. Liu’s research interest is to design and synthesize organic molecules and organic/inorganic hybrid materials and explore their applications in chemo/bio-sensors and optoelectronic devices. Dr. Liu is the winner of NUS Young Investigator Award 2006 and National Science and Technology Young Scientist Award 2008. Dr. Liu has more than 70 research papers and 15 patents.
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