題目：Nanostructured and Electroactive Materials for Biotechnology and Tissue Engineering
報(bào)告人：Prof. Wei Yen（Department of Chemistry, Drexel University, USA）
日期及時(shí)間：2009 年9 月10 日15 時(shí)00 分
地點(diǎn)：研－411
報(bào)告內(nèi)容摘要（不多于300字）：
We have developed a novel, biocompatible nonsurfactant-templating pathway to nanoporous metal oxides with high surface area (~1000 m2/g) and pore volume (~1.0 cm3/g) as well as pore size in the range of 2-15 nm with narrow pore size distribution. The nonsurfactant molecules, such as glucose, dibenzoyl tartaric acid, fructose, cyclodextrins, urea, glycerol, etc., are used as templates to direct the mesostructure formation in sol-gel reactions. The entire preparation can be performed at room temperature and neutral pH. Such a novel materials platform has enabled us to encapsulate a variety of bioactive substances including enzymes, proteins, nucleic acids and therapeutic agents directly in nanoporous host materials for biocatalysis, biosensor, drug release, nanobioreactor, and enzyme therapy applications. It also provides a new tool to study protein behavior in confined space, including protein folding and protein-protein interactions as well as protein aggregations as in Alzheimer’s and Parkinson’s diseases. The nanoporous materials have also been employed as fillers for the synthesis of nanocomposite and dental materials. In addition, electroactive polymers have been used as intelligent scaffolds for neural, cardiac and stem cell tissue engineering
報(bào)告人簡(jiǎn)介（不多于200字）：
Dr. Yen Wei received BS (1979) and MS (1981) in Chemistry at Peking University in China. He then earned his PhD from the City University of New York in 1986. After postdoctoral work at MIT, he joined Drexel University in 1987, where he is currently the Herman B. Wagner Professor of Chemistry and Director of the Center for Advanced Polymers and Materials Chemistry. Dr. Wei has contributed to various fields of polymer, materials, and biological chemistry. He has co-edited 2 books, co-authored 440 scientific articles (> 6100 citations), and held 10 issued US patents. Among the awards Dr. Wei received include the ACS Philadelphia Section Award, Drexel Research Achievement Award, and DuPont Young Faculty Award. Dr. Wei has also been appointed Guest Professor at 16 universities in China. He was a Visiting Fellow at Princeton University. In 2006, he was honored with an endowed Chang Jiang Lecture-Chair Professorship at Shanghai Jiao Tong University in China.
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