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短桿菌肽 A 是短桿菌肽的肽成分,短桿菌肽是一種最初從短桿菌中分離的抗生素混合物。
編號(hào):200496
CAS號(hào):11029-61-1
單字母:For-VGAlAvVvWlWlWlW-NHCH2CH2OH
Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 α (HIF-1α).
Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 α (HIF-1α).
很多蛋白在細(xì)胞中非常容易被降解,或被標(biāo)記,進(jìn)而被選擇性地破壞。但含有部分D型氨基酸的多肽則顯示了很強(qiáng)的抵抗蛋白酶降解能力。
DOI | 名稱 | |
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10.1021/la026717c | Cholesterol-Modulated Lipid−Peptide Communication in Fluid Bilayers | 下載 |